› 1jjx

Solution NMR

Solution Structure of Recombinant Human Brain-type Fatty acid Binding Protein

Released:
DOI: 10.2210/pdb1jjx/pdb
PDB entry 1jjx coloured by chain, ensemble of 20 models, front view.
PDB entry 1jjx coloured by chain, ensemble of 20 models, side view.
PDB entry 1jjx coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of fatty acid-binding protein from human brain.
Rademacher M, Zimmerman AW, Rüterjans H, Veerkamp JH, Lücke C
Mol Cell Biochem 239 61-8 (2002)
PMID: 12479569

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127524 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid-binding protein, brain Chain: A
Molecule details ›
Chain: A
Length: 131 amino acids
Theoretical weight: 14.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O15540 (Residues: 2-132; Coverage: 99%)
Gene names: BLBP, FABP7, FABPB, MRG
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: TORSION ANGLE DYNAMICS COMBINED WITH SIMULATED ANNEALING FOLLOWED BY ENERGY MINIMIZATION
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

New technologies for drug delivery across the blood brain barrier.
Kabanov et al. (2004)
1 more

4 mentions without citation

The two sides of a lipid-protein story.
Basso et al. (2016)
3 more