PDBe 1irh

Solution NMR

The Solution Structure of The Third Kunitz Domain of Tissue Factor Pathway Inhibitor

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tissue factor pathway inhibitor Chain: A
Molecule details ›
Chain: A
Length: 61 amino acids
Theoretical weight: 6.92 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P10646 (Residues: 210-270; Coverage: 22%)
Gene names: LACI, TFPI, TFPI1
Sequence domains: Kunitz/Bovine pancreatic trypsin inhibitor domain
Structure domains: Pancreatic trypsin inhibitor Kunitz domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Komagataella pastoris