1ib2

X-ray diffraction
1.9Å resolution

CRYSTAL STRUCTURE OF A PUMILIO-HOMOLOGY DOMAIN

Released:
Source organism: Homo sapiens
Primary publication:
Crystal structure of a Pumilio homology domain.
Mol. Cell 7 855-65 (2001)
PMID: 11336708

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pumilio homolog 1 Chain: A
Molecule details ›
Chain: A
Length: 349 amino acids
Theoretical weight: 40.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q14671 (Residues: 828-1176; Coverage: 29%)
Gene names: KIAA0099, PUM1, PUMH1
Sequence domains: Pumilio-family RNA binding repeat
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: R32
Unit cell:
a: 142.88Å b: 142.88Å c: 111.31Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.198 0.198 0.242
Expression system: Escherichia coli BL21(DE3)