PDBe 1i4l

X-ray diffraction
2.7Å resolution

CRYSTAL STRUCTURE ANALYSIS OF RAC1-GDP IN COMPLEX WITH ARFAPTIN (P41)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Arfaptin-2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 224 amino acids
Theoretical weight: 25.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Best match: P53365 (Residues: 118-341)
Gene names: ARFIP2, POR1
Ras-related C3 botulinum toxin substrate 1 Chain: D
Molecule details ›
Chain: D
Length: 192 amino acids
Theoretical weight: 21.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Best match: P63000 (Residues: 1-192)
Gene names: MIG5, RAC1, TC25

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P41
Unit cell:
a: 112.379Å b: 112.379Å c: 68.242Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.258 0.258 0.301
Expression system: Escherichia coli