Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154047 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Interleukin-6 receptor subunit beta
Molecule details ›
Chain: A
Length: 303 amino acids
Theoretical weight: 34.66 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Structure domains: Immunoglobulins
Length: 303 amino acids
Theoretical weight: 34.66 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P40189 (Residues: 23-325; Coverage: 34%)
Sequence domains:
Structure domains: Immunoglobulins
Interleukin-6 homolog
Molecule details ›
Chain: B
Length: 181 amino acids
Theoretical weight: 20.86 KDa
Source organism: Human gammaherpesvirus 8
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Interleukin-6/G-CSF/MGF family
Structure domains: Growth Hormone; Chain: A;
Length: 181 amino acids
Theoretical weight: 20.86 KDa
Source organism: Human gammaherpesvirus 8
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: Q98823 (Residues: 24-204; Coverage: 89%)
Sequence domains: Interleukin-6/G-CSF/MGF family
Structure domains: Growth Hormone; Chain: A;
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ALS BEAMLINE 5.0.2
Spacegroup:
C2
Expression system: Spodoptera frugiperda
