1hlu

X-ray diffraction
2.65Å resolution

STRUCTURE OF BOVINE BETA-ACTIN-PROFILIN COMPLEX WITH ACTIN BOUND ATP PHOSPHATES SOLVENT ACCESSIBLE

Released:
Source organism: Bos taurus
Primary publication:
The structure of an open state of beta-actin at 2.65 A resolution.
J. Mol. Biol. 263 607-23 (1996)
PMID: 8918942

Function and Biology Details

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Actin, cytoplasmic 1 Chain: A
Molecule details ›
Chain: A
Length: 375 amino acids
Theoretical weight: 41.69 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P60712 (Residues: 2-375; Coverage: 100%)
Gene name: ACTB
Sequence domains: Actin
Structure domains:
Profilin-1 Chain: P
Molecule details ›
Chain: P
Length: 140 amino acids
Theoretical weight: 14.97 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P02584 (Residues: 2-140; Coverage: 99%)
Gene name: PFN1
Sequence domains: Profilin
Structure domains: Dynein light chain 2a, cytoplasmic

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P212121
Unit cell:
a: 38.14Å b: 72.24Å c: 185.7Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.201 0.33