1hkl

X-ray diffraction
2.68Å resolution

FREE AND LIGANDED FORM OF AN ESTEROLYTIC CATALYTIC ANTIBODY

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Immunoglobulin kappa constant Chain: L
Molecule details ›
Chain: L
Length: 214 amino acids
Theoretical weight: 23.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P01834 (Residues: 1-107; Coverage: 100%)
Gene name: IGKC
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Immunoglobulin heavy constant gamma 1 Chain: H
Molecule details ›
Chain: H
Length: 217 amino acids
Theoretical weight: 23.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P01857 (Residues: 1-103; Coverage: 31%)
Gene name: IGHG1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 138.69Å b: 44.49Å c: 84.95Å
α: 90° β: 121.75° γ: 90°
R-values:
R R work R free
0.184 0.184 0.244
Expression system: Escherichia coli BL21