› 1gzt

X-ray diffraction
1.3Å resolution

Pseudomonas aeruginosa lectin II (PA-IIL) together with fucose

Released:
DOI: 10.2210/pdb1gzt/pdb
PDB entry 1gzt coloured by chain, front view.
PDB entry 1gzt coloured by chain, side view.
PDB entry 1gzt coloured by chain, top view.
Source organism: Pseudomonas aeruginosa
Primary publication:
Structural basis for oligosaccharide-mediated adhesion of Pseudomonas aeruginosa in the lungs of cystic fibrosis patients.
Mitchell E, Houles C, Sudakevitz D, Wimmerova M, Gautier C, Pérez S, Wu AM, Gilboa-Garber N, Imberty A
Nat Struct Biol 9 918-21 (2002)
PMID: 12415289

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191159 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium-mediated lectin domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 115 amino acids
Theoretical weight: 11.87 KDa
Source organism: Pseudomonas aeruginosa
UniProt:
  • Canonical: Q9HYN5 (Residues: 1-115; Coverage: 100%)
Gene names: PA3361, lecB
Sequence domains: Fucose-binding lectin II (PA-IIL)
Structure domains: Calcium-mediated lectin

Ligands and Environments

2 bound ligands:
Ligand FUC 4 x FUC
Ligand CA 8 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P21
Unit cell:
a: 52.66Å b: 72.92Å c: 54.56Å
α: 90° β: 94.23° γ: 90°
R-values:
R R work R free
0.137 0.136 0.158

Quick links

Citations

23 review citations

Mucins, mucus, and sputum.
Voynow et al. (2009)
22 more

9 mentions without citation

From carbohydrate leads to glycomimetic drugs.
Ernst et al. (2009)
8 more