› 1g4i

X-ray diffraction
0.97Å resolution

Crystal structure of the bovine pancreatic phospholipase A2 at 0.97A

Released:
DOI: 10.2210/pdb1g4i/pdb
PDB entry 1g4i coloured by chain, front view.
PDB entry 1g4i coloured by chain, side view.
PDB entry 1g4i coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
X-ray structure of bovine pancreatic phospholipase A2 at atomic resolution.
Steiner RA, Rozeboom HJ, de Vries A, Kalk KH, Murshudov GN, Wilson KS, Dijkstra BW
Acta Crystallogr D Biol Crystallogr 57 516-26 (2001)
PMID: 11264580

Function and Biology Details

Reaction catalysed: 
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132750 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phospholipase A2 Chain: A
Molecule details ›
Chain: A
Length: 123 amino acids
Theoretical weight: 13.81 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00593 (Residues: 23-145; Coverage: 95%)
Gene name: PLA2G1B
Sequence domains: Phospholipase A2
Structure domains: Phospholipase A2 domain

Ligands and Environments

4 bound ligands:
Ligand CA 1 x CA
Ligand CL 1 x CL
Ligand MRD 3 x MRD
Ligand MPD 2 x MPD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P212121
Unit cell:
a: 46.532Å b: 63.557Å c: 37.624Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.094 0.094 not available

Quick links

Citations

3 review citations

The interfacial binding surface of phospholipase A2s.
Winget et al. (2006)
2 more

8 mentions without citation

Macromolecular ab initio phasing enforcing secondary and tertiary structure.
Millán et al. (2015)
7 more