PDBe 1g0n

X-ray diffraction
2Å resolution

STRUCTURE OF TRIHYDROXYNAPHTHALENE REDUCTASE IN COMPLEX WITH NADPH AND 4,5,6,7-TETRACHLORO-PHTHALIDE

Released:

Function and Biology Details

Reaction catalysed:
Scytalone + NADP(+) = 1,3,6,8-tetrahydroxynaphthalene + NADPH
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tetrahydroxynaphthalene reductase Chains: A, B
Molecule details ›
Chains: A, B
Length: 283 amino acids
Theoretical weight: 30.18 KDa
Source organism: Magnaporthe grisea
Expression system: Escherichia coli
UniProt:
  • Canonical: Q12634 (Residues: 1-283; Coverage: 100%)
Gene name: MGG_02252
Sequence domains:
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments


Cofactor: Ligand NDP 2 x NDP
1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P3121
Unit cell:
a: 140.5Å b: 140.5Å c: 72.7Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.195 0.195 0.244
Expression system: Escherichia coli