1fy8

X-ray diffraction
1.7Å resolution

CRYSTAL STRUCTURE OF THE DELTAILE16VAL17 RAT ANIONIC TRYPSINOGEN-BPTI COMPLEX

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Anionic trypsin-2 Chain: E
Molecule details ›
Chain: E
Length: 231 amino acids
Theoretical weight: 24.74 KDa
Source organism: Rattus rattus
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P00763 (Residues: 14-246; Coverage: 99%)
Gene names: Prss2, Try2
Structure domains: Trypsin-like serine proteases
Pancreatic trypsin inhibitor Chain: I
Molecule details ›
Chain: I
Length: 58 amino acids
Theoretical weight: 6.53 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00974 (Residues: 36-93; Coverage: 73%)
Sequence domains: Kunitz/Bovine pancreatic trypsin inhibitor domain
Structure domains: Pancreatic trypsin inhibitor Kunitz domain

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P3221
Unit cell:
a: 92.6Å b: 92.6Å c: 62.06Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.183 0.183 0.214
Expression system: Saccharomyces cerevisiae