1fng

X-ray diffraction
1.9Å resolution

HISTOCOMPATIBILITY ANTIGEN

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero tetramer
hetero octamer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
H-2 class II histocompatibility antigen, E-K alpha chain Chains: A, C
Molecule details ›
Chains: A, C
Length: 192 amino acids
Theoretical weight: 22.36 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P04224 (Residues: 26-217; Coverage: 84%)
Sequence domains:
Structure domains:
Hemoglobin subunit beta-2; Ig-like domain-containing protein Chains: B, D
Molecule details ›
Chains: B, D
Length: 224 amino acids
Theoretical weight: 25.38 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P02089 (Residues: 65-77; Coverage: 9%)
  • Canonical: Q31163 (Residues: 29-224; Coverage: 82%)
Gene names: H2-Eb1, Hbb-b2
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2
Unit cell:
a: 147.14Å b: 57.024Å c: 116.809Å
α: 90° β: 91.97° γ: 90°
R-values:
R R work R free
0.221 0.221 0.254
Expression system: Spodoptera frugiperda