X-ray diffraction
1.6Å resolution

Crystal structure of the TPR1 domain of HOP in complex with a HSC70 peptide


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Stress-induced-phosphoprotein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 118 amino acids
Theoretical weight: 13.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P31948 (Residues: 1-118; Coverage: 22%)
Gene name: STIP1
Structure domains: Tetratricopeptide repeat domain
HSC70-PEPTIDE Chains: C, D
Molecule details ›
Chains: C, D
Length: 8 amino acids
Theoretical weight: 859 Da
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12B
Spacegroup: P41
Unit cell:
a: 75.47Å b: 75.47Å c: 42.89Å
α: 90° β: 90° γ: 90°
R R work R free
0.18 0.18 0.215
Expression systems:
  • Escherichia coli
  • Not provided