1elr

X-ray diffraction
1.9Å resolution

Crystal structure of the TPR2A domain of HOP in complex with the HSP90 peptide MEEVD

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Stress-induced-phosphoprotein 1 Chain: A
Molecule details ›
Chain: A
Length: 131 amino acids
Theoretical weight: 15.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P31948 (Residues: 223-352; Coverage: 24%)
Gene name: STIP1
Sequence domains:
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
DSCR1 Chain: B
Molecule details ›
Chain: B
Length: 6 amino acids
Theoretical weight: 648 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9H2A1 (Residues: 1-5; Coverage: 17%)

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-3
Spacegroup: C2
Unit cell:
a: 73.28Å b: 48.27Å c: 38.06Å
α: 90° β: 91.3° γ: 90°
R-values:
R R work R free
0.181 0.181 0.219
Expression systems:
  • Escherichia coli
  • Not provided