1e4u

Solution NMR

N-terminal RING finger domain of human NOT-4

Released:

Function and Biology Details

Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CCR4-NOT transcription complex subunit 4 Chain: A
Molecule details ›
Chain: A
Length: 78 amino acids
Theoretical weight: 9.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O95628 (Residues: 1-78; Coverage: 14%)
Gene names: CNOT4, NOT4
Sequence domains: RING/Ubox like zinc-binding domain
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shifts: BMR4621  
Expression system: Escherichia coli