1cf8

X-ray diffraction
2.7Å resolution

Convergence of catalytic antibody and terpene cyclase mechanisms: polyene cyclization directed by carbocation-pi interactions

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero tetramer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Immunoglobulin kappa constant Chain: L
Molecule details ›
Chain: L
Length: 215 amino acids
Theoretical weight: 23.48 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01837 (Residues: 1-107; Coverage: 100%)
Gene name: Igkc
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Ig gamma-2B chain C region Chain: H
Molecule details ›
Chain: H
Length: 218 amino acids
Theoretical weight: 23.5 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01867 (Residues: 1-98; Coverage: 24%)
Gene name: Igh-3
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: C2
Unit cell:
a: 101.3Å b: 70.3Å c: 69.6Å
α: 90° β: 114.2° γ: 90°
R-values:
R R work R free
0.165 0.165 0.257