› 1ce3

Solution NMR

PUTATIVE ANCESTRAL PROTEIN ENCODED BY A SINGLE SEQUENCE REPEAT OF THE MULTIDOMAIN PROTEINASE INHIBITOR FROM NICOTIANA ALATA

Released:
DOI: 10.2210/pdb1ce3/pdb
PDB entry 1ce3 coloured by chain, ensemble of 20 models, front view.
PDB entry 1ce3 coloured by chain, ensemble of 20 models, side view.
PDB entry 1ce3 coloured by chain, ensemble of 20 models, top view.
Source organism: Nicotiana alata
Primary publication:
Structure of a putative ancestral protein encoded by a single sequence repeat from a multidomain proteinase inhibitor gene from Nicotiana alata.
Scanlon MJ, Lee MC, Anderson MA, Craik DJ
Structure 7 793-802 (1999)
PMID: 10425681

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174930 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proteinase inhibitor Chain: A
Molecule details ›
Chain: A
Length: 54 amino acids
Theoretical weight: 5.93 KDa
Source organism: Nicotiana alata
Expression system: Escherichia coli
UniProt:
  • Canonical: Q40378 (Residues: 88-140; Coverage: 14%)
Sequence domains: Potato type II proteinase inhibitor family
Structure domains: Wheat Germ Agglutinin (Isolectin 2); domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Evolutionary mechanisms acting on proteinase inhibitor variability.
Christeller JT. (2005)
2 more

4 mentions without citation

Search for allosteric disulfide bonds in NMR structures.
Schmidt et al. (2007)
3 more