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Solution NMR

How an Epidermal Growth Factor (EGF)-Like Domain Binds Calcium-High Resolution NMR Structure of the Calcium Form of the NH2-Terminal EGF-Like Domain in Coagulation Factor X

Released:

Function and Biology Details

Reaction catalysed:
Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin to form thrombin.
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133220 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Factor X light chain Chain: A
Molecule details ›
Chain: A
Length: 42 amino acids
Theoretical weight: 4.58 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P00743 (Residues: 85-126; Coverage: 9%)
Gene name: F10
Sequence domains: EGF-like domain
Structure domains: Laminin

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided