› 1c4e

Solution NMR

GURMARIN FROM GYMNEMA SYLVESTRE

Released:
DOI: 10.2210/pdb1c4e/pdb
PDB entry 1c4e coloured by chain, ensemble of 20 models, front view.
PDB entry 1c4e coloured by chain, ensemble of 20 models, side view.
PDB entry 1c4e coloured by chain, ensemble of 20 models, top view.
Source organism: Gymnema sylvestre
Primary publication:
High-resolution solution structure of gurmarin, a sweet-taste-suppressing plant polypeptide.
Fletcher JI, Dingley AJ, Smith R, Connor M, Christie MJ, King GF
Eur J Biochem 264 525-33 (1999)
PMID: 10491100

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150589 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gurmarin Chain: A
Molecule details ›
Chain: A
Length: 35 amino acids
Theoretical weight: 4.22 KDa
Source organism: Gymnema sylvestre
UniProt:
  • Canonical: P25810 (Residues: 1-35; Coverage: 100%)

Ligands and Environments

No bound ligands
1 modified residue:
Ligand PCA 1 x PCA

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY AND DYNAMICAL SIMULATED ANNEALING

Quick links

Citations

6 review citations

The cystine knot motif in toxins and implications for drug design.
Craik et al. (2001)
5 more

2 mentions without citation

Identification of distant Agouti-like sequences and re-evaluation of the evolutionary history of the Agouti-related peptide (AgRP).
Västermark et al. (2012)
1 more