1c2b

X-ray diffraction
4.5Å resolution

ELECTROPHORUS ELECTRICUS ACETYLCHOLINESTERASE

Released:

Function and Biology Details

Reaction catalysed:
Acetylcholine + H(2)O = choline + acetate

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Acetylcholinesterase Chain: A
Molecule details ›
Chain: A
Length: 540 amino acids
Theoretical weight: 59.42 KDa
Source organism: Electrophorus electricus
UniProt:
  • Canonical: P21836 (Residues: 35-574; Coverage: 93%)
Gene name: Ache
Sequence domains: Carboxylesterase family

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: F222
Unit cell:
a: 117.98Å b: 215.87Å c: 229.41Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.369 0.369 0.351