1bzq

X-ray diffraction
2.8Å resolution

COMPLEX OF A DROMEDARY SINGLE-DOMAIN VHH ANTIBODY FRAGMENT WITH RNASE A

Released:

Function and Biology Details

Reaction catalysed:
(1a) an (RNA) containing cytidine = an (RNA)-3'-cytidine-2',3'-cyclophosphate + a 5'-hydroxy-ribonucleotide-3'-(RNA)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-225767 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ribonuclease pancreatic Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 124 amino acids
Theoretical weight: 13.71 KDa
Source organism: Bos taurus
UniProt:
  • Best match: P61823 (Residues: 27-150)
Gene names: RNASE1, RNS1
PROTEIN (ANTIBODY CAB-RN05) Chains: K, L, M, N
Molecule details ›
Chains: K, L, M, N
Length: 124 amino acids
Theoretical weight: 13.33 KDa
Source organism: Camelus dromedarius
Expression system: Escherichia coli

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P1
Unit cell:
a: 66.52Å b: 66.82Å c: 69.34Å
α: 91.43° β: 117.34° γ: 97.33°
R-values:
R R work R free
0.222 0.222 0.282
Expression system: Escherichia coli