1bxx

X-ray diffraction
2.7Å resolution

MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH TGN38 INTERNALIZATION PEPTIDE DYQRLN

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
AP-2 complex subunit mu Chain: A
Molecule details ›
Chain: A
Length: 285 amino acids
Theoretical weight: 32.76 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P84092 (Residues: 158-435; Coverage: 64%)
Gene name: Ap2m1
Sequence domains: Adaptor complexes medium subunit family
Structure domains: Immunoglobulin-like
PROTEIN (TGN38 PEPTIDE) Chain: P
Molecule details ›
Chain: P
Length: 6 amino acids
Theoretical weight: 809 Da
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: P64
Unit cell:
a: 125.26Å b: 125.26Å c: 73.79Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.282 0.263 0.325
Expression systems:
  • Escherichia coli BL21
  • Not provided