› 1blf

X-ray diffraction
2.8Å resolution

STRUCTURE OF DIFERRIC BOVINE LACTOFERRIN AT 2.8 ANGSTROMS RESOLUTION

Released:
DOI: 10.2210/pdb1blf/pdb
PDB 1blf coloured by chain and viewed from the front.
PDB 1blf coloured by chain and viewed from the side.
PDB 1blf coloured by chain and viewed from the top.
Source organism: Bos taurus
Primary publication:
Three-dimensional structure of diferric bovine lactoferrin at 2.8 A resolution.
Moore SA, Anderson BF, Groom CR, Haridas M, Baker EN
J. Mol. Biol. 274 222-36 (1997)
PMID: 9398529

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Lactotransferrin Chain: A
Molecule details ›
Chain: A
Length: 689 amino acids
Theoretical weight: 76.24 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P24627 (Residues: 20-708; Coverage: 100%)
Gene name: LTF
Sequence domains: Transferrin
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
3 bound ligands:
Ligand NAG 1 x NAG
Ligand FE 2 x FE
Ligand CO3 2 x CO3
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P212121
Unit cell:
a: 138.86Å b: 87.01Å c: 73.35Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.232 0.217 0.28

Quick links

Citations

31 review citations

Lactoferrin-Conjugated Nanoparticles as New Antivirals.
Krzyzowska et al. (2022)
30 more

37 mentions without citation

Antimicrobial Peptide Mimics for Clinical Use: Does Size Matter?
Svenson et al. (2022)
36 more