› 1b88

X-ray diffraction
2.5Å resolution

V-ALPHA 2.6 MOUSE T CELL RECEPTOR (TCR) DOMAIN

Released:
DOI: 10.2210/pdb1b88/pdb
PDB entry 1b88 coloured by chain, front view.
PDB entry 1b88 coloured by chain, side view.
PDB entry 1b88 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
The X-ray crystal structure of a Valpha2.6Jalpha38 mouse T cell receptor domain at 2.5 A resolution: alternate modes of dimerization and crystal packing.
Plaksin D, Chacko S, Navaza J, Margulies DH, Padlan EA
J Mol Biol 289 1153-61 (1999)
PMID: 10373358

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177772 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ig-like domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 114 amino acids
Theoretical weight: 12.7 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5R1B3 (Residues: 28-120; Coverage: 94%)
Gene name: TRAV14-3
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 53.987Å b: 76.187Å c: 88.402Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.224 0.324
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

How TCRs bind MHCs, peptides, and coreceptors.
Rudolph et al. (2006)
1 more

3 mentions without citation

Prototypic T cell receptor and CD4-like coreceptor are expressed by lymphocytes in the agnathan sea lamprey.
Pancer et al. (2004)
2 more