1aqc

X-ray diffraction
2.3Å resolution

X11 PTB DOMAIN-10MER PEPTIDE COMPLEX

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
Non-polymer only tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Amyloid-beta A4 precursor protein-binding family A member 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 172 amino acids
Theoretical weight: 19.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q02410 (Residues: 453-623; Coverage: 20%)
Gene names: APBA1, MINT1, X11
Sequence domains: Phosphotyrosine interaction domain (PTB/PID)
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
PEPTIDE Chains: C, D
Molecule details ›
Chains: C, D
Length: 10 amino acids
Theoretical weight: 1.27 KDa
Source organism: Homo sapiens

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P41212
Unit cell:
a: 74.4Å b: 74.4Å c: 157.1Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.21 0.303
Expression system: Escherichia coli