1aox

X-ray diffraction
2.1Å resolution

I DOMAIN FROM INTEGRIN ALPHA2-BETA1

Released:
Source organism: Homo sapiens
Primary publication:
Crystal structure of the I domain from integrin alpha2beta1.
J. Biol. Chem. 272 28512-7 (1997)
PMID: 9353312

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Integrin alpha-2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 203 amino acids
Theoretical weight: 22.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P17301 (Residues: 169-365, 366-367; Coverage: 17%)
Gene names: CD49B, ITGA2
Sequence domains: von Willebrand factor type A domain
Structure domains: von Willebrand factor, type A domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P1
Unit cell:
a: 40.54Å b: 43.29Å c: 68.04Å
α: 88.27° β: 76.59° γ: 66.74°
R-values:
R R work R free
0.219 0.219 not available
Expression system: Escherichia coli BL21