1agq

X-ray diffraction
1.9Å resolution

GLIAL CELL-DERIVED NEUROTROPHIC FACTOR FROM RAT

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glial cell line-derived neurotrophic factor Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 135 amino acids
Theoretical weight: 15.09 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q07731 (Residues: 78-211; Coverage: 70%)
Gene name: Gdnf
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P21
Unit cell:
a: 67.85Å b: 67.55Å c: 71.4Å
α: 90° β: 115.94° γ: 90°
R-values:
R R work R free
0.203 0.203 0.235
Expression system: Escherichia coli