Function and Biology Details
Biochemical function:
Biological process:
- not assigned
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Insulin A chain
Molecule details ›
Chain: A
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
- Canonical:
P01308 (Residues: 90-110; Coverage: 24%)
Insulin B chain
Molecule details ›
Chain: B
Length: 29 amino acids
Theoretical weight: 3.21 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
Length: 29 amino acids
Theoretical weight: 3.21 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
- Canonical: P01308 (Residues: 25-53; Coverage: 34%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
DISTANCE GEOMETRY AND SIMULATED ANNEALING
Expression system: Saccharomyces cerevisiae
