PDBe 1a3l

X-ray diffraction
1.95Å resolution

CATALYSIS OF A DISFAVORED REACTION: AN ANTIBODY EXO DIELS-ALDERASE-TSA-INHIBITOR COMPLEX AT 1.95 A RESOLUTION

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Immunoglobulin kappa constant Chain: L
Molecule details ›
Chain: L
Length: 217 amino acids
Theoretical weight: 23.81 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01837 (Residues: 1-105; Coverage: 98%)
Gene name: Igkc
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Ig gamma-1 chain C region, membrane-bound form Chain: H
Molecule details ›
Chain: H
Length: 218 amino acids
Theoretical weight: 23.2 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01869 (Residues: 1-99; Coverage: 25%)
Gene names: Igh-4, Ighg1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: C2
Unit cell:
a: 182.9Å b: 40.5Å c: 67.7Å
α: 90° β: 109° γ: 90°
R-values:
R R work R free
0.188 not available 0.265