EMD-9931 Function and Biology

Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1 state class1)

Single particle reconstruction
3.3Å resolution
Overview of EMD-9931
Sample name: ATP8A1-CDC50a
Number of unique components: 5

ATP8A1-CDC50a [Homo sapiens]

Protein type
Name: ATP8A1-CDC50a
Expression system
Expression system: Homo sapiens
Cell line: Expi293F
Vector: pcDNA3.4

Phospholipid-transporting ATPase [Homo sapiens]

Protein type
Name: Phospholipid-transporting ATPase
Theoretical weight (MDa): 0.131
Number of copies: 1
Expression system
Expression system: Homo sapiens

Cell cycle control protein 50A [Homo sapiens]

Protein type
Name: Cell cycle control protein 50A
Theoretical weight (MDa): 0.041
Number of copies: 1
Expression system
Expression system: Homo sapiens

2-acetamido-2-deoxy-beta-D-glucopyranose

Ligand type
Name: 2-acetamido-2-deoxy-beta-D-glucopyranose
Theoretical weight (MDa): 0
Number of copies: 2

CHOLESTEROL HEMISUCCINATE

Ligand type
Name: CHOLESTEROL HEMISUCCINATE
Theoretical weight (MDa): 0
Number of copies: 1