EMD-4787 Function and Biology

D. melanogaster CMG-DNA with ATP, State 2A

Single particle reconstruction
4.28Å resolution
Overview of EMD-4787
Sample name: CMG helicase bound to forked DNA in the presence of ATP, State 2A
Number of unique components: 17

CMG helicase bound to forked DNA in the presence of ATP, State 2A

Protein type
Name: CMG helicase bound to forked DNA in the presence of ATP, State 2A

CMG helicase [Drosophila melanogaster]

Protein type
Name: CMG helicase
Expression system
Expression system: Trichoplusia ni

DNA [Drosophila melanogaster]

Protein type
Name: DNA
Expression system
Expression system: synthetic construct

DNA replication licensing factor Mcm3 [Drosophila melanogaster]

Protein type
Name: DNA replication licensing factor Mcm3
Theoretical weight (MDa): 0.091
Number of copies: 1
Expression system
Expression system: Trichoplusia ni

DNA replication licensing factor MCM4 [Drosophila melanogaster]

Protein type
Name: DNA replication licensing factor MCM4
Theoretical weight (MDa): 0.097
Number of copies: 1
Expression system
Expression system: Trichoplusia ni

DNA replication licensing factor Mcm7 [Drosophila melanogaster]

Protein type
Name: DNA replication licensing factor Mcm7
Theoretical weight (MDa): 0.081
Number of copies: 1
Expression system
Expression system: Trichoplusia ni

DNA replication licensing factor Mcm6 [Drosophila melanogaster]

Protein type
Name: DNA replication licensing factor Mcm6
Theoretical weight (MDa): 0.092
Number of copies: 1
Expression system
Expression system: Trichoplusia ni

DNA replication licensing factor Mcm5 [Drosophila melanogaster]

Protein type
Name: DNA replication licensing factor Mcm5
Theoretical weight (MDa): 0.082
Number of copies: 1
Expression system
Expression system: Trichoplusia ni

CDC45L [Drosophila melanogaster]

Protein type
Name: CDC45L
Theoretical weight (MDa): 0.066
Number of copies: 1
Expression system
Expression system: Trichoplusia ni

IP07275p [Drosophila melanogaster]

Protein type
Name: IP07275p
Theoretical weight (MDa): 0.023
Number of copies: 1
Expression system
Expression system: Trichoplusia ni

Probable DNA replication complex GINS protein PSF2 [Drosophila melanogaster]

Protein type
Name: Probable DNA replication complex GINS protein PSF2
Theoretical weight (MDa): 0.023
Number of copies: 1
Expression system
Expression system: Trichoplusia ni

AT18545p [Drosophila melanogaster]

Protein type
Name: AT18545p
Theoretical weight (MDa): 0.025
Number of copies: 1
Expression system
Expression system: Trichoplusia ni

DNA replication complex GINS protein SLD5 [Drosophila melanogaster]

Protein type
Name: DNA replication complex GINS protein SLD5
Theoretical weight (MDa): 0.026
Number of copies: 1
Expression system
Expression system: Trichoplusia ni

DNA replication licensing factor Mcm2 [Drosophila melanogaster]

Protein type
Name: DNA replication licensing factor Mcm2
Theoretical weight (MDa): 0.101
Number of copies: 1
Expression system
Expression system: Trichoplusia ni

DNA (5'-D(P*AP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3') [Drosophila melanogaster]

Nucleic-acid type
Name: DNA (5'-D(P*AP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3')
Theoretical weight (MDa): 0.004
Type: DNA
Structure: OTHER
Synthetic: false
Sequence: (DA)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DT)

ADENOSINE-5'-TRIPHOSPHATE

Ligand type
Name: ADENOSINE-5'-TRIPHOSPHATE
Theoretical weight (MDa): 0.001
Number of copies: 4

ADENOSINE-5'-DIPHOSPHATE

Ligand type
Name: ADENOSINE-5'-DIPHOSPHATE
Theoretical weight (MDa): 0
Number of copies: 2