EMD-4259
Cryo-EM structure of F-actin in complex with ADP-Pi
EMD-4259
Single-particle3.3 Å
Deposition: 15/01/2018
Map released: 13/06/2018
Last modified: 29/08/2018
Name: Filamentous alpha actin in complex with ADP-ADPPi
Summary:
Filamentous alpha actin in complex with ADP-ADPPi
Name: Natural source [1]
Organism: Oryctolagus cuniculus
Actin, alpha skeletal muscle
Number of copies: 5
UniProtKB PDBe-KB AlphaFold DB
Name: Number of copies: 5
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [29]
Biological process:
skeletal muscle fiber development mesenchyme migration skeletal muscle thin filament assembly actin filament polymerization actin filament bundle assembly positive regulation of gene expression
Molecular function:
hydrolase activity titin binding tropomyosin binding identical protein binding magnesium ion binding myosin heavy chain binding cytoskeletal motor activator activity troponin I binding ATP binding protein domain specific binding calcium-dependent protein binding actin monomer binding calcium ion binding
Cellular location:
skeletal muscle myofibril lamellipodium filopodium filamentous actin striated muscle thin filament stress fiber actin filament bundle cytoplasm actin filament cell body
skeletal muscle fiber development mesenchyme migration skeletal muscle thin filament assembly actin filament polymerization actin filament bundle assembly positive regulation of gene expression
Molecular function:
hydrolase activity titin binding tropomyosin binding identical protein binding magnesium ion binding myosin heavy chain binding cytoskeletal motor activator activity troponin I binding ATP binding protein domain specific binding calcium-dependent protein binding actin monomer binding calcium ion binding
Cellular location:
skeletal muscle myofibril lamellipodium filopodium filamentous actin striated muscle thin filament stress fiber actin filament bundle cytoplasm actin filament cell body
Natural source
Molecular weight
Experimental | Theoretical | Method |
---|---|---|
- | 41 kDa | - |
ADENOSINE-5'-DIPHOSPHATE
HET code: ADP
Number of copies: 5
ChEMBL ChEBI DrugBank
Name: HET code: ADP
Number of copies: 5
ChEMBL ChEBI DrugBank
Molecular weight
Experimental | Theoretical | Method |
---|---|---|
- | 427 Da | - |
MAGNESIUM ION
HET code: MG
Number of copies: 5
ChEBI DrugBank
Name: HET code: MG
Number of copies: 5
ChEBI DrugBank
Molecular weight
Experimental | Theoretical | Method |
---|---|---|
- | 24 Da | - |
PHOSPHATE ION
HET code: PO4
Number of copies: 5
ChEBI DrugBank
Name: HET code: PO4
Number of copies: 5
ChEBI DrugBank
Molecular weight
Experimental | Theoretical | Method |
---|---|---|
- | 94 Da | - |