EMD-30421

Single-particle
3.0 Å
EMD-30421
3D View Gallery
Deposition: 06/08/2020
Map released: 28/04/2021
Last modified: 27/03/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-30421
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Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
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EMICSS annotations (xml)

Cryo-EM structure of human mitochondrial translocase TOM complex at 3.o angstrom.

EMD-30421

Single-particle
3.0 Å
EMD-30421
3D View Gallery
Deposition: 06/08/2020
Map released: 28/04/2021
Last modified: 27/03/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Name: TOM translocase
Complex [1]
Name: TOM translocase
Natural source [1]
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 440.0 kDa/nm -
Complex Portal [1]
ID Name Overlap
CPX-6121 TOM40 mitochondrial outer membrane translocase complex 0.71
Protein [5]
LEVO
Name: Mitochondrial import receptor subunit TOM5 homolog
Number of copies: 2
UniProtKB UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [7]
Biological process:
protein insertion into mitochondrial outer membrane protein targeting to mitochondrion

Cellular location:
TOM complex mitochondrion mitochondrial outer membrane translocase complex integral component of membrane mitochondrial outer membrane
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 6 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
LEVO
Name: Mitochondrial import receptor subunit TOM6 homolog
Number of copies: 2
UniProtKB UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [6]
Biological process:
protein insertion into mitochondrial outer membrane protein transport

Cellular location:
TOM complex mitochondrion mitochondrial outer membrane translocase complex mitochondrial outer membrane
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 8 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
LEVO
Name: Mitochondrial import receptor subunit TOM7 homolog
Number of copies: 2
UniProtKB UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [12]
Biological process:
protein insertion into mitochondrial outer membrane positive regulation of protein targeting to mitochondrion protein targeting to mitochondrion positive regulation of mitophagy in response to mitochondrial depolarization regulation of protein stability protein import into mitochondrial matrix
Molecular function:
protein transmembrane transporter activity
Cellular location:
TOM complex mitochondrial outer membrane translocase complex mitochondrial outer membrane mitochondrion integral component of membrane
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 6 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
LEVO
Name: Mitochondrial import receptor subunit TOM22 homolog
Number of copies: 2
UniProtKB UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [10]
Biological process:
positive regulation of apoptotic process protein insertion into mitochondrial outer membrane protein targeting to mitochondrion
Molecular function:
protein transmembrane transporter activity
Cellular location:
TOM complex integral component of membrane mitochondrial outer membrane mitochondrial outer membrane translocase complex membrane mitochondrion
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 15 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
LEVO
Name: Mitochondrial import receptor subunit TOM40 homolog
Number of copies: 2
UniProtKB UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [18]
Biological process:
monoatomic ion transport protein insertion into mitochondrial outer membrane protein targeting to mitochondrion protein import into mitochondrial matrix ion transport
Molecular function:
porin activity protein transmembrane transporter activity
Cellular location:
TOM complex membrane pore complex mitochondrial inner membrane mitochondria-associated endoplasmic reticulum membrane cytosol mitochondrial outer membrane translocase complex mitochondrial outer membrane integral component of membrane mitochondrion integral component of mitochondrial outer membrane
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 37 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Ligand [1]
Name: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE
HET code: PC1
Number of copies: 11
ChEBI
Molecular weight
Experimental Theoretical Method
- 790 Da -