EMD-22009 Function and Biology

Structure of human TRPA1 in complex with agonist GNE551

Single particle reconstruction
3.0Å resolution
Overview of EMD-22009
Sample name: TRPA1 bound by agonist GNE551
Number of unique components: 3

TRPA1 bound by agonist GNE551 [Homo sapiens]

Protein type
Name: TRPA1 bound by agonist GNE551
Expression system
Expression system: Spodoptera frugiperda

Transient receptor potential cation channel subfamily A member 1 [Homo sapiens]

Protein type
Name: Transient receptor potential cation channel subfamily A member 1
Theoretical weight (MDa): 0.073
Number of copies: 4
Expression system
Expression system: Spodoptera frugiperda

5-amino-1-[(4-bromo-2-fluorophenyl)methyl]-N-(2,5-dimethoxyphenyl)-1H-1,2,3-triazole-4-carboxamide

Ligand type
Name: 5-amino-1-[(4-bromo-2-fluorophenyl)methyl]-N-(2,5-dimethoxyphenyl)-1H-1,2,3-triazole-4-carboxamide
Theoretical weight (MDa): 0
Number of copies: 4