EMD-21512 Function and Biology

Cryo-EM structure of 5HT3A receptor in presence of Ondansetron

Single particle reconstruction
3.06Å resolution
Overview of EMD-21512
Sample name: Serotonin receptor
Number of unique components: 3

Serotonin receptor [Mus musculus]

Protein type
Name: Serotonin receptor
Theoretical weight (MDa): 0.27
Expression system
Expression system: Spodoptera frugiperda

5-hydroxytryptamine receptor 3A [Mus musculus]

Protein type
Name: 5-hydroxytryptamine receptor 3A
Theoretical weight (MDa): 0.052
Number of copies: 5
Expression system
Expression system: Spodoptera frugiperda

ondansetron

Ligand type
Name: ondansetron
Theoretical weight (MDa): 0
Number of copies: 5