EMD-21512

Single-particle
3.06 Å
EMD-21512
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Deposition: 04/03/2020
Map released: 13/01/2021
Last modified: 13/01/2021
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Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-21512
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6w1m summary report (pdf.gz) Map and 6w1m FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of 5HT3A receptor in presence of Ondansetron

EMD-21512

Single-particle
3.06 Å
EMD-21512
3D View Gallery
Deposition: 04/03/2020
Map released: 13/01/2021
Last modified: 13/01/2021
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Name: Serotonin receptor
Complex [1]
Name: Serotonin receptor
Natural source [1]
Organism: Mus musculus
Recombinant Expression [1]
Organism Strain Cell Plasmid
Spodoptera frugiperda - - -
Molecular weight
Experimental Theoretical Method
- 270 kDa -
Complex Portal [1]
ID Name Overlap
CPX-274 5-hydroxytryptamine-3A receptor complex 1.00
Protein [1]
LEVO
Name: 5-hydroxytryptamine receptor 3A
Number of copies: 5
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [17]
Biological process:
inorganic cation transmembrane transport serotonin receptor signaling pathway
Molecular function:
serotonin-gated monoatomic cation channel activity serotonin binding ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential identical protein binding acetylcholine-gated monoatomic cation-selective channel activity serotonin-gated monoatomic cation-selective channel activity
Cellular location:
synapse cleavage furrow axon presynaptic membrane glutamatergic synapse serotonin-activated cation-selective channel complex neuron projection neuronal cell body postsynaptic membrane
Natural source
Organism: Mus musculus
Molecular weight
Experimental Theoretical Method
- 52 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Spodoptera frugiperda - - -
Ligand [1]
Name: ondansetron
HET code: S87
Number of copies: 5
ChEMBL ChEBI DrugBank
Molecular weight
Experimental Theoretical Method
- 293 Da -