EMD-20490 Function and Biology

Human alpha3beta4 nicotinic acetylcholine receptor in complex with AT-1001 in saposin nanodiscs

Single particle reconstruction
4.55Å resolution
Overview of EMD-20490
Sample name: Human alpha3beta4 nicotinic receptor in complex with Fab fragments and bound to AT-1001
Number of unique components: 1
Details: Fab fragments generated by proteolytic cleavage of IgG antibody

Human alpha3beta4 nicotinic receptor in complex with Fab fragments and bound to AT-1001 [Homo sapiens]

Protein type
Name: Human alpha3beta4 nicotinic receptor in complex with Fab fragments and bound to AT-1001
Expression system
Expression system: Homo sapiens