EMD-20175

Single-particle
4.05 Å
EMD-20175
3D View Gallery
Deposition: 30/04/2019
Map released: 12/06/2019
Last modified: 25/11/2020
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-20175
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6orn summary report (pdf.gz) Map and 6orn FULL report (pdf.gz)
EMICSS annotations (xml)

Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch bNAb 10-1074

EMD-20175

Single-particle
4.05 Å
EMD-20175
3D View Gallery
Deposition: 30/04/2019
Map released: 12/06/2019
Last modified: 25/11/2020
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Name: Complex of RC1 variant of BG505 SOSIP.664 trimer with three 10-1074 Fabs and three CD4bs Fabs
Complex [3]
Name: Complex of RC1 variant of BG505 SOSIP.664 trimer with three 10-1074 Fabs and three CD4bs Fabs
Details: Fab fragments generated by recombinant expression and complexed with the RC1 variant of BG505 SOSIP.664 trimer
Natural source [1]
Organism: Human immunodeficiency virus 1
Molecular weight
Experimental Theoretical Method
- 600 kDa -
Name: RC1 variant of BG505 SOSIP.664 trimer
Natural source [1]
Organism: Human immunodeficiency virus 1
Recombinant Expression [1]
Organism Strain Cell Plasmid
Homo sapiens - Expi293 -
Name: 10-1074 Fab
Natural source [1]
Organism: Homo sapiens
Recombinant Expression [1]
Organism Strain Cell Plasmid
Homo sapiens - Expi293 -
Protein [4]
LEVO
Name: RC1 variant of HIV-1 Env glycoprotein gp41
Number of copies: 3
Natural source
Organism: Human immunodeficiency virus 1
Molecular weight
Experimental Theoretical Method
- 17 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
LEVO
Name: RC1 variant of HIV-1 Env glycoprotein gp120
Number of copies: 3
Natural source
Organism: Human immunodeficiency virus 1
Molecular weight
Experimental Theoretical Method
- 54 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
LEVO
Name: 10-1074 antibody Fab heavy chain
Number of copies: 3
UniProtKB PDBe-KB AlphaFold DB
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 25 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
LEVO
Name: 10-1074 antibody Fab light chain
Number of copies: 3
UniProtKB PDBe-KB AlphaFold DB
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 23 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Ligand [1]
Name: 2-acetamido-2-deoxy-beta-D-glucopyranose
HET code: NAG
Number of copies: 30
ChEMBL ChEBI
Molecular weight
Experimental Theoretical Method
- 221 Da -