EMD-12865

Single-particle
2.2 Å
EMD-12865
3D View Gallery
Deposition: 04/05/2021
Map released: 09/06/2021
Last modified: 30/06/2021
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-12865
Download
3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7of0 summary report (pdf.gz) Map and 7of0 FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with MTERF4-NSUN4 (dataset1).

EMD-12865

Single-particle
2.2 Å
EMD-12865
3D View Gallery
Deposition: 04/05/2021
Map released: 09/06/2021
Last modified: 30/06/2021
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Name: Human mitochondrial ribosome large subunit assembly intermediate in complex with MTERF4-NSUN4 (dataset1).
Summary:
Complex [1]
Name: Human mitochondrial ribosome large subunit assembly intermediate in complex with MTERF4-NSUN4 (dataset1).
Natural source [1]
Organism: Homo sapiens
Strain: HEK293-Flp-In T-Rex
Organelle: Mitochondria
Complex Portal [2]
ID Name Overlap
CPX-5226 39S mitochondrial large ribosomal subunit 0.79
CPX-5226 39S mitochondrial large ribosomal subunit 0.82
Protein [54]
LEVO
Name: 39S ribosomal protein L32, mitochondrial
Number of copies: 1
UniProtKB UniProtKB PDBe-KB PDBe-KB AlphaFold DB AlphaFold DB
Domains
Gene Ontology [8]
Biological process:
mitochondrial translation translation
Molecular function:
structural constituent of ribosome RNA binding
Cellular location:
mitochondrial ribosome mitochondrial inner membrane mitochondrion mitochondrial large ribosomal subunit
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 21 kDa -
LEVO
Name: 39S ribosomal protein L33, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [6]
Biological process:
mitochondrial translation translation
Molecular function:
structural constituent of ribosome
Cellular location:
mitochondrial large ribosomal subunit mitochondrial inner membrane mitochondrion
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 7 kDa -
LEVO
Name: 39S ribosomal protein L34, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [7]
Biological process:
mitochondrial translation translation
Molecular function:
structural constituent of ribosome
Cellular location:
mitochondrion mitochondrial large ribosomal subunit mitochondrial ribosome mitochondrial inner membrane
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 10 kDa -
LEVO
Name: 39S ribosomal protein L35, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [7]
Biological process:
mitochondrial translation translation
Molecular function:
structural constituent of ribosome
Cellular location:
mitochondrion mitochondrial ribosome mitochondrial inner membrane mitochondrial large ribosomal subunit
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 21 kDa -
LEVO
Name: 39S ribosomal protein L36, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [8]
Biological process:
mitochondrial translation ribosome biogenesis translation
Molecular function:
structural constituent of ribosome
Cellular location:
mitochondrial large ribosomal subunit nuclear body mitochondrial inner membrane mitochondrion
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 11 kDa -
LEVO
Name: 39S ribosomal protein L37, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [8]
Biological process:
mitochondrial translation translation
Molecular function:
RNA binding structural constituent of ribosome
Cellular location:
mitochondrial large ribosomal subunit mitochondrial ribosome mitochondrial inner membrane mitochondrion
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 48 kDa -
LEVO
Name: 39S ribosomal protein L38, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [5]
Biological process:
mitochondrial translation

Cellular location:
cytosol mitochondrial inner membrane mitochondrial large ribosomal subunit mitochondrion
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 44 kDa -
LEVO
Name: 39S ribosomal protein L39, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [7]
Biological process:
mitochondrial translation
Molecular function:
RNA binding nucleotide binding
Cellular location:
mitochondrial inner membrane mitochondrial ribosome mitochondrion mitochondrial large ribosomal subunit
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 38 kDa -
LEVO
Name: 39S ribosomal protein L40, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [9]
Biological process:
mitochondrial translation anatomical structure morphogenesis
Molecular function:
RNA binding
Cellular location:
mitochondrial ribosome mitochondrial large ribosomal subunit mitochondrial inner membrane mitochondrion nucleus nucleolus
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 24 kDa -
LEVO
Name: 39S ribosomal protein L41, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [10]
Biological process:
mitochondrial translation translation apoptotic process cell cycle
Molecular function:
structural constituent of ribosome RNA binding
Cellular location:
mitochondrial inner membrane ribonucleoprotein complex mitochondrion mitochondrial large ribosomal subunit
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 15 kDa -
LEVO
Name: 5-methylcytosine rRNA methyltransferase NSUN4
EC number: 2.1.1.-
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [9]
Biological process:
RNA methylation rRNA methylation
Molecular function:
tRNA (cytidine-5-)-methyltransferase activity rRNA methyltransferase activity rRNA binding methyltransferase activity rRNA (cytosine-C5-)-methyltransferase activity
Cellular location:
mitochondrial large ribosomal subunit mitochondrial matrix
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 43 kDa -
LEVO
Name: 39S ribosomal protein L2, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 33 kDa -
LEVO
Name: 39S ribosomal protein L3, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [7]
Biological process:
mitochondrial translation translation
Molecular function:
structural constituent of ribosome RNA binding
Cellular location:
mitochondrial large ribosomal subunit mitochondrial inner membrane mitochondrion
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 38 kDa -
LEVO
Name: 39S ribosomal protein L4, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [7]
Biological process:
mitochondrial translation translation
Molecular function:
RNA binding structural constituent of ribosome
Cellular location:
mitochondrial large ribosomal subunit mitochondrion mitochondrial inner membrane
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 34 kDa -
LEVO
Name: Transcription termination factor 4, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [15]
Biological process:
regulation of DNA-templated transcription mitochondrial ribosome assembly camera-type eye development rRNA processing regulation of transcription, DNA-templated heart development ribosome assembly protein targeting to mitochondrion mitochondrial transcription
Molecular function:
rRNA binding double-stranded DNA binding
Cellular location:
mitochondrial large ribosomal subunit mitochondrion cytosol mitochondrial matrix
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 44 kDa -
LEVO
Name: 39S ribosomal protein L9, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [8]
Biological process:
mitochondrial translation translation
Molecular function:
RNA binding structural constituent of ribosome
Cellular location:
mitochondrial large ribosomal subunit mitochondrial inner membrane mitochondrion mitochondrial ribosome
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 30 kDa -
LEVO
Name: 39S ribosomal protein L10, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [10]
Biological process:
mitochondrial translation translation
Molecular function:
structural constituent of ribosome RNA binding
Cellular location:
nucleoplasm mitochondrion large ribosomal subunit mitochondrial large ribosomal subunit ribonucleoprotein complex mitochondrial inner membrane
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 29 kDa -
LEVO
Name: 39S ribosomal protein L11, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [10]
Biological process:
mitochondrial translation translation
Molecular function:
large ribosomal subunit rRNA binding RNA binding structural constituent of ribosome
Cellular location:
mitochondrion mitochondrial inner membrane large ribosomal subunit mitochondrial large ribosomal subunit mitochondrial ribosome
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 20 kDa -
LEVO
Name: 39S ribosomal protein L13, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [11]
Biological process:
mitochondrial translation translation negative regulation of translation
Molecular function:
structural constituent of ribosome mRNA binding RNA binding
Cellular location:
mitochondrial large ribosomal subunit mitochondrial inner membrane mitochondrial ribosome mitochondrion ribosome
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 20 kDa -
LEVO
Name: 39S ribosomal protein L14, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [7]
Biological process:
mitochondrial translation translation
Molecular function:
RNA binding structural constituent of ribosome
Cellular location:
mitochondrial inner membrane mitochondrial large ribosomal subunit mitochondrion
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 15 kDa -
LEVO
Name: 39S ribosomal protein L15, mitochondrial
Number of copies: 1
UniProtKB UniProtKB PDBe-KB PDBe-KB AlphaFold DB AlphaFold DB
Domains
Gene Ontology [8]
Biological process:
mitochondrial translation cellular response to leukemia inhibitory factor translation
Molecular function:
structural constituent of ribosome RNA binding
Cellular location:
mitochondrion mitochondrial large ribosomal subunit mitochondrial inner membrane
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 33 kDa -
LEVO
Name: 39S ribosomal protein L16, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [6]
Biological process:
mitochondrial translation
Molecular function:
structural constituent of ribosome rRNA binding
Cellular location:
mitochondrion mitochondrial inner membrane mitochondrial large ribosomal subunit
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 28 kDa -
LEVO
Name: 39S ribosomal protein L17, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [8]
Biological process:
mitochondrial translation translation
Molecular function:
structural constituent of ribosome protein domain specific binding
Cellular location:
large ribosomal subunit mitochondrial large ribosomal subunit mitochondrion mitochondrial inner membrane
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 20 kDa -
LEVO
Name: 39S ribosomal protein L18, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [10]
Biological process:
mitochondrial translation rRNA import into mitochondrion translation
Molecular function:
structural constituent of ribosome 5S rRNA binding
Cellular location:
mitochondrial large ribosomal subunit mitochondrial ribosome mitochondrial inner membrane mitochondrion extracellular space
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 20 kDa -
LEVO
Name: 39S ribosomal protein L19, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [7]
Biological process:
mitochondrial translation translation
Molecular function:
structural constituent of ribosome
Cellular location:
mitochondrial large ribosomal subunit mitochondrial inner membrane nucleus mitochondrion
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 33 kDa -
LEVO
Name: 39S ribosomal protein L20, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [10]
Biological process:
mitochondrial translation ribosomal large subunit assembly translation
Molecular function:
RNA binding rRNA binding structural constituent of ribosome
Cellular location:
mitochondrial ribosome mitochondrial large ribosomal subunit mitochondrion mitochondrial inner membrane
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 17 kDa -
LEVO
Name: 39S ribosomal protein L21, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [7]
Biological process:
mitochondrial translation translation
Molecular function:
RNA binding structural constituent of ribosome
Cellular location:
mitochondrial inner membrane mitochondrial large ribosomal subunit mitochondrion
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 22 kDa -
LEVO
Name: 39S ribosomal protein L22, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [9]
Biological process:
mitochondrial translation translation ribosome assembly
Molecular function:
structural constituent of ribosome RNA binding
Cellular location:
mitochondrial large ribosomal subunit large ribosomal subunit mitochondrion mitochondrial inner membrane
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 23 kDa -
LEVO
Name: 39S ribosomal protein L23, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [8]
Biological process:
translation mitochondrial translation
Molecular function:
RNA binding structural constituent of ribosome
Cellular location:
fibrillar center mitochondrion mitochondrial inner membrane mitochondrial large ribosomal subunit
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 17 kDa -
LEVO
Name: 39S ribosomal protein L24, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [7]
Biological process:
mitochondrial translation translation
Molecular function:
RNA binding structural constituent of ribosome
Cellular location:
mitochondrion mitochondrial inner membrane mitochondrial large ribosomal subunit
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 24 kDa -
LEVO
Name: 39S ribosomal protein L27, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 16 kDa -
LEVO
Name: 39S ribosomal protein L28, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [9]
Biological process:
mitochondrial translation translation
Molecular function:
RNA binding structural constituent of ribosome
Cellular location:
mitochondrial inner membrane mitochondrial ribosome mitochondrion mitochondrial large ribosomal subunit cytosol
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 30 kDa -
LEVO
Name: 39S ribosomal protein L47, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [5]
Biological process:
mitochondrial translation
Molecular function:
structural constituent of ribosome
Cellular location:
mitochondrial large ribosomal subunit mitochondrion mitochondrial inner membrane
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 29 kDa -
LEVO
Name: 39S ribosomal protein L30, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [6]
Biological process:
mitochondrial translation translation
Molecular function:
structural constituent of ribosome
Cellular location:
mitochondrion mitochondrial inner membrane mitochondrial large ribosomal subunit
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 18 kDa -
LEVO
Name: 39S ribosomal protein L42, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [9]
Biological process:
mitochondrial translation translation
Molecular function:
RNA binding structural constituent of ribosome
Cellular location:
mitochondrial large ribosomal subunit mitochondrial small ribosomal subunit mitochondrial inner membrane mitochondrion plasma membrane
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 16 kDa -
LEVO
Name: 39S ribosomal protein L43, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [8]
Biological process:
translation mitochondrial translation
Molecular function:
structural constituent of ribosome RNA binding
Cellular location:
mitochondrial ribosome mitochondrial inner membrane mitochondrial large ribosomal subunit mitochondrion
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 23 kDa -
LEVO
Name: 39S ribosomal protein L44, mitochondrial
EC number: 3.1.26.-
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [17]
Biological process:
rRNA processing mitochondrial translation mitochondrial translational elongation rRNA catabolic process RNA processing
Molecular function:
RNA binding structural constituent of ribosome endonuclease activity double-stranded RNA binding
Cellular location:
nucleus microprocessor complex plasma membrane mitochondrial inner membrane mitochondrial large ribosomal subunit mitochondrion nuclear body nucleoplasm
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 37 kDa -
LEVO
Name: 39S ribosomal protein L45, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [5]
Biological process:
mitochondrial translation
Molecular function:
RNA binding
Cellular location:
mitochondrial large ribosomal subunit mitochondrial inner membrane mitochondrion
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 35 kDa -
LEVO
Name: 39S ribosomal protein L46, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [7]
Biological process:
mitochondrial translation
Molecular function:
structural constituent of ribosome
Cellular location:
mitochondrial large ribosomal subunit nucleoplasm mitochondrion cell junction mitochondrial inner membrane
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 31 kDa -
LEVO
Name: 39S ribosomal protein L48, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [5]
Biological process:
mitochondrial translation

Cellular location:
mitochondrial large ribosomal subunit mitochondrial inner membrane mitochondrion mitochondrial ribosome
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 23 kDa -
LEVO
Name: 39S ribosomal protein L49, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [7]
Biological process:
mitochondrial translation translation
Molecular function:
structural constituent of ribosome
Cellular location:
mitochondrial inner membrane mitochondrial ribosome mitochondrion mitochondrial large ribosomal subunit
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 19 kDa -
LEVO
Name: 39S ribosomal protein L50, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [5]
Biological process:
mitochondrial translation

Cellular location:
cytosol mitochondrial inner membrane mitochondrial large ribosomal subunit mitochondrion
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 18 kDa -
LEVO
Name: 39S ribosomal protein L51, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [7]
Biological process:
translation mitochondrial translation
Molecular function:
structural constituent of ribosome
Cellular location:
mitochondrial inner membrane mitochondrial ribosome mitochondrion mitochondrial large ribosomal subunit
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 15 kDa -
LEVO
Name: 39S ribosomal protein L52, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [7]
Biological process:
translation mitochondrial translation
Molecular function:
structural constituent of ribosome
Cellular location:
mitochondrial inner membrane nucleoplasm mitochondrial large ribosomal subunit mitochondrion
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 13 kDa -
LEVO
Name: 39S ribosomal protein L53, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [4]
Biological process:
mitochondrial translation

Cellular location:
mitochondrial inner membrane mitochondrial large ribosomal subunit mitochondrion
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 12 kDa -
LEVO
Name: 39S ribosomal protein L55, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [7]
Biological process:
mitochondrial translation translation
Molecular function:
structural constituent of ribosome
Cellular location:
synapse mitochondrial inner membrane mitochondrial large ribosomal subunit mitochondrion
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 15 kDa -
LEVO
Name: Ribosomal protein 63, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [6]
Biological process:
mitochondrial translation
Molecular function:
structural constituent of ribosome
Cellular location:
mitochondrion mitochondrial ribosome mitochondrial inner membrane mitochondrial large ribosomal subunit
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 12 kDa -
LEVO
Name: Peptidyl-tRNA hydrolase ICT1, mitochondrial
EC number: 3.1.1.29
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [11]
Biological process:
rescue of stalled ribosome mitochondrial translation mitochondrial translational termination
Molecular function:
aminoacyl-tRNA hydrolase activity translation release factor activity, codon nonspecific
Cellular location:
plasma membrane nucleoplasm mitochondrion mitochondrial inner membrane mitochondrial large ribosomal subunit mitochondrial matrix
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 23 kDa -
LEVO
Name: Growth arrest and DNA damage-inducible proteins-interacting protein 1
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [8]
Biological process:
mitochondrial translation cell cycle

Cellular location:
mitochondrial inner membrane mitochondrial large ribosomal subunit mitochondrion nucleoplasm mitochondrial matrix ribosome
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 25 kDa -
LEVO
Name: 39S ribosomal protein S18a, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [8]
Biological process:
mitochondrial translation translation
Molecular function:
small ribosomal subunit rRNA binding structural constituent of ribosome
Cellular location:
mitochondrion mitochondrial small ribosomal subunit mitochondrial large ribosomal subunit mitochondrial inner membrane
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 22 kDa -
LEVO
Name: 39S ribosomal protein S30, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [8]
Biological process:
mitochondrial translation apoptotic process translation
Molecular function:
RNA binding structural constituent of ribosome
Cellular location:
mitochondrial large ribosomal subunit mitochondrion mitochondrial inner membrane
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 50 kDa -
LEVO
Name: Mitochondrial assembly of ribosomal large subunit protein 1
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [9]
Biological process:
ribosomal large subunit biogenesis negative regulation of mitochondrial translation negative regulation of translation negative regulation of ribosome biogenesis
Molecular function:
mitochondrial large ribosomal subunit binding ribosomal large subunit binding
Cellular location:
mitochondrial matrix mitochondrion cytosol
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 26 kDa -
LEVO
Name: MIEF1 upstream open reading frame protein
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [9]
Biological process:
mitochondrial large ribosomal subunit assembly mitochondrial fission mitochondrial respiratory chain complex I assembly cellular response to hypoxia ribosome biogenesis positive regulation of mitochondrial translation
Molecular function:
mitochondrial large ribosomal subunit binding
Cellular location:
mitochondrial matrix mitochondrion
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 8 kDa -
LEVO
Name: Acyl carrier protein, mitochondrial
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [21]
Biological process:
[2Fe-2S] cluster assembly proton motive force-driven mitochondrial ATP synthesis aerobic respiration iron-sulfur cluster assembly mitochondrial ATP synthesis coupled proton transport fatty acid biosynthetic process mitochondrial respiratory chain complex I assembly protein lipoylation mitochondrial electron transport, NADH to ubiquinone
Molecular function:
mitochondrial large ribosomal subunit binding acyl carrier activity calcium ion binding acyl binding fatty acid binding
Cellular location:
iron-sulfur cluster assembly complex mitochondrial respiratory chain complex I nucleoplasm mitochondrial matrix mitochondrion mitochondrial inner membrane mitochondrial membrane
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 17 kDa -
RNA [2]
Name: 16S ribosomal RNA
Number of copies: 1
Natural source
Organism: Human
Molecular weight
Experimental Theoretical Method
- 500 kDa -
Name: mitochondrial tRNAVal
Number of copies: 1
Natural source
Organism: human
Molecular weight
Experimental Theoretical Method
- 22 kDa -
Ligand [2]
Name: ZINC ION
HET code: ZN
Number of copies: 3
ChEMBL ChEBI DrugBank
Molecular weight
Experimental Theoretical Method
- 65 Da -
Name: MAGNESIUM ION
HET code: MG
Number of copies: 61
ChEBI DrugBank
Molecular weight
Experimental Theoretical Method
- 24 Da -