Human mitochondrial ribosome in complex with mRNA, A/A tRNA and P/P tRNA
Single particle
reconstruction
2.59Å resolution
2.59Å resolution
Sample name:
Ribosome with mRNA and tRNAs
Number of unique components:
97
Details:
Mitochondrial ribosome in complex with mRNA, A/A tRNA and P/P tRNA
Ribosome with mRNA and tRNAs [Homo sapiens]
Protein type
Name:
Ribosome with mRNA and tRNAs
Theoretical weight (MDa):
2
Large subunit of ribosome [Homo sapiens]
Protein type
Name:
Large subunit of ribosome
Small subunit of ribosome [Homo sapiens]
Protein type
Name:
Small subunit of ribosome
16S mitochondrial rRNA [Human]
Nucleic-acid type
Name:
16S mitochondrial rRNA
Theoretical weight (MDa):
0.501
Type:
RNA
Structure:
OTHER
Synthetic:
false
Sequence:
GCUAAACCUAGCCCCAAACCCACUCCACCUUACUACCAGACAACCUUAGCCAAACCAUUUACCCAAAUAAAGUAUAGGCG AUAGAAAUUGAAACCUGGCGCAAUAGAUAUAGUACCGCAAGGGAAAGAUGAAAAAUUAUAACCAAGCAUAAUAUAGCAAG GACUAACCCCUAUACCUUCUGCAUAAUGAAUUAACUAGAAAUAACUUUGCAAGGAGAGCCAAAGCUAAGACCCCCGAAAC CAGACGAGCUACCUAAGAACAGCUAAAAGAGCACACCCGUCUAUGUAGCAAAAUAGUGGGAAGAUUUAUAGGUAGAGGCG ACAAACCUACCGAGCCUGGUGAUAGCUGGUUGUCCAAGAUAGAAUCUUAGUUCAACUUUAAAUUUGCCCACAGAACCCUC UAAAUCCCCUUGUAAAUUUAACUGUUAGUCCAAAGAGGAACAGCUCUUUGGACACUAGGAAAAAACCUUGUAGAGAGAGU AAAAAAUUUAACACCCAUAGUAGGCCUAAAAGCAGCCACCAAUUAAGAAAGCGUUCAAGCUCAACACCCACUACCUAAAA AAUCCCAAACAUAUAACUGAACUCCUCACACCCAAUUGGACCAAUCUAUCACCCUAUAGAAGAACUAAUGUUAGUAUAAG UAACAUGAAAACAUUCUCCUCCGCAUAAGCCUGCGUCAGAUUAAAACACUGAACUGACAAUUAACAGCCCAAUAUCUACA AUCAACCAACAAGUCAUUAUUACCCUCACUGUCAACCCAACACAGGCAUGCUCAUAAGGAAAGGUUAAAAAAAGUAAAAG GAACUCGGCAAAUCUUACCCCGCCUGUUUACCAAAAACAUCACCUCUAGCAUCACCAGUAUUAGAGGCACCGCCUGCCCA GUGACACAUGUUUAACGGCCGCGGUACCCUAACCGUGCAAAGGUAGCAUAAUCACUUGUUCCUUAAAUAGGGACCUGUAU GAAUGGCUCCACGAGGGUUCAGCUGUCUCUUACUUUUAACCAGUGAAAUUGACCUGCCCGUGAAGAGGCGGGCAUAACAC AGCAAGACGAGAAGACCCUAUGGAGCUUUAAUUUAUUAAUGCAAACAGUACCUAACAAACCCACAGGUCCUAAACUACCA AACCUGCAUUAAAAAUUUCGGUUGGGGCGACCUCGGAGCAGAACCCAACCUCCGAGCAGUACAUGCUAAGACUUCACCAG UCAAAGCGAACUACUAUACUCAAUUGAUCCAAUAACUUGACCAACGGAACAAGUUACCCUAGGGAUAACAGCGCAAUCCU AUUCUAGAGUCCAUAUCAACAAUAGGGUUUACGACCUCGAUGUUGGAUCAGGACAUCCCGAUGGUGCAGCCGCUAUUAAA GGUUCGUUUGUUCAACGAUUAAAGUCCUACGUGAUCUGAGUUCAGACCGGAGUAAUCCAGGUCGGUUUCUAUCUACUUUC AAAUUCCUCCCUGUACGAAAGGACAAGAGAAAUAAGGCCUACUUCACAAAGCGCCUUCCCCCGUAAAUGAUAUCAUCUCA ACUUAGUAUUAUACCCACACCCACCCAAGAACAGGGUUUGU
mitochondrial tRNAVal [Human]
Nucleic-acid type
Name:
mitochondrial tRNAVal
Theoretical weight (MDa):
0.023
Type:
RNA
Structure:
OTHER
Synthetic:
false
Sequence:
CAGAGUGUAGCUUAACACAAAGCACCCAACUUACACUUAGGAGAUUUCAACUUAACUUGACCGCUCUGACCA
39S ribosomal protein L2, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L2, mitochondrial
Theoretical weight (MDa):
0.033
Number of copies:
1
39S ribosomal protein L3, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L3, mitochondrial
Theoretical weight (MDa):
0.039
Number of copies:
1
39S ribosomal protein L4, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L4, mitochondrial
Theoretical weight (MDa):
0.035
Number of copies:
1
39S ribosomal protein L9, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L9, mitochondrial
Theoretical weight (MDa):
0.03
Number of copies:
1
39S ribosomal protein L10, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L10, mitochondrial
Theoretical weight (MDa):
0.029
Number of copies:
1
39S ribosomal protein L11, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L11, mitochondrial
Theoretical weight (MDa):
0.021
Number of copies:
1
39S ribosomal protein L13, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L13, mitochondrial
Theoretical weight (MDa):
0.021
Number of copies:
1
39S ribosomal protein L14, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L14, mitochondrial
Theoretical weight (MDa):
0.016
Number of copies:
1
39S ribosomal protein L15, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L15, mitochondrial
Theoretical weight (MDa):
0.033
Number of copies:
1
39S ribosomal protein L16, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L16, mitochondrial
Theoretical weight (MDa):
0.028
Number of copies:
1
39S ribosomal protein L17, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L17, mitochondrial
Theoretical weight (MDa):
0.02
Number of copies:
1
39S ribosomal protein L18, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L18, mitochondrial
Theoretical weight (MDa):
0.021
Number of copies:
1
39S ribosomal protein L19, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L19, mitochondrial
Theoretical weight (MDa):
0.034
Number of copies:
1
39S ribosomal protein L20, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L20, mitochondrial
Theoretical weight (MDa):
0.017
Number of copies:
1
39S ribosomal protein L21, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L21, mitochondrial
Theoretical weight (MDa):
0.023
Number of copies:
1
39S ribosomal protein L22, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L22, mitochondrial
Theoretical weight (MDa):
0.024
Number of copies:
1
39S ribosomal protein L23, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L23, mitochondrial
Theoretical weight (MDa):
0.018
Number of copies:
1
39S ribosomal protein L24, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L24, mitochondrial
Theoretical weight (MDa):
0.025
Number of copies:
1
39S ribosomal protein L27, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L27, mitochondrial
Theoretical weight (MDa):
0.016
Number of copies:
1
39S ribosomal protein L28, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L28, mitochondrial
Theoretical weight (MDa):
0.03
Number of copies:
1
39S ribosomal protein L47, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L47, mitochondrial
Theoretical weight (MDa):
0.03
Number of copies:
1
39S ribosomal protein L30, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L30, mitochondrial
Theoretical weight (MDa):
0.019
Number of copies:
1
39S ribosomal protein L32, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L32, mitochondrial
Theoretical weight (MDa):
0.021
Number of copies:
1
39S ribosomal protein L33, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L33, mitochondrial
Theoretical weight (MDa):
0.008
Number of copies:
1
39S ribosomal protein L34, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L34, mitochondrial
Theoretical weight (MDa):
0.01
Number of copies:
1
39S ribosomal protein L35, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L35, mitochondrial
Theoretical weight (MDa):
0.022
Number of copies:
1
39S ribosomal protein L36, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L36, mitochondrial
Theoretical weight (MDa):
0.012
Number of copies:
1
39S ribosomal protein L37, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L37, mitochondrial
Theoretical weight (MDa):
0.048
Number of copies:
1
39S ribosomal protein L38, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L38, mitochondrial
Theoretical weight (MDa):
0.045
Number of copies:
1
39S ribosomal protein L39, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L39, mitochondrial
Theoretical weight (MDa):
0.039
Number of copies:
1
39S ribosomal protein L40, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L40, mitochondrial
Theoretical weight (MDa):
0.025
Number of copies:
1
39S ribosomal protein L41, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L41, mitochondrial
Theoretical weight (MDa):
0.015
Number of copies:
1
39S ribosomal protein L42, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L42, mitochondrial
Theoretical weight (MDa):
0.017
Number of copies:
1
39S ribosomal protein L43, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L43, mitochondrial
Theoretical weight (MDa):
0.023
Number of copies:
1
39S ribosomal protein L44, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L44, mitochondrial
Theoretical weight (MDa):
0.038
Number of copies:
1
39S ribosomal protein L45, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L45, mitochondrial
Theoretical weight (MDa):
0.035
Number of copies:
1
39S ribosomal protein L46, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L46, mitochondrial
Theoretical weight (MDa):
0.032
Number of copies:
1
39S ribosomal protein L48, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L48, mitochondrial
Theoretical weight (MDa):
0.024
Number of copies:
1
39S ribosomal protein L49, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L49, mitochondrial
Theoretical weight (MDa):
0.019
Number of copies:
1
39S ribosomal protein L50, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L50, mitochondrial
Theoretical weight (MDa):
0.018
Number of copies:
1
39S ribosomal protein L51, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L51, mitochondrial
Theoretical weight (MDa):
0.015
Number of copies:
1
39S ribosomal protein L52, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L52, mitochondrial
Theoretical weight (MDa):
0.014
Number of copies:
1
39S ribosomal protein L53, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L53, mitochondrial
Theoretical weight (MDa):
0.012
Number of copies:
1
39S ribosomal protein L54, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L54, mitochondrial
Theoretical weight (MDa):
0.016
Number of copies:
1
39S ribosomal protein L55, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L55, mitochondrial
Theoretical weight (MDa):
0.015
Number of copies:
1
Ribosomal protein 63, mitochondrial [Human]
Protein type
Name:
Ribosomal protein 63, mitochondrial
Theoretical weight (MDa):
0.012
Number of copies:
1
Peptidyl-tRNA hydrolase ICT1, mitochondrial [Human]
Protein type
Name:
Peptidyl-tRNA hydrolase ICT1, mitochondrial
Theoretical weight (MDa):
0.024
Number of copies:
1
Growth arrest and DNA damage-inducible proteins-interacting protein 1 [Human]
Protein type
Name:
Growth arrest and DNA damage-inducible proteins-interacting protein 1
Theoretical weight (MDa):
0.025
Number of copies:
1
39S ribosomal protein S18a, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein S18a, mitochondrial
Theoretical weight (MDa):
0.022
Number of copies:
1
39S ribosomal protein S30, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein S30, mitochondrial
Theoretical weight (MDa):
0.05
Number of copies:
1
39S ribosomal protein L12, mitochondrial [Human]
Protein type
Name:
39S ribosomal protein L12, mitochondrial
Theoretical weight (MDa):
0.021
Number of copies:
6
12S mitochondrial rRNA [Human]
Nucleic-acid type
Name:
12S mitochondrial rRNA
Theoretical weight (MDa):
0.306
Type:
RNA
Structure:
OTHER
Synthetic:
false
Sequence:
AUAGGUUUGGUCCUAGCCUUUCUAUUAGCUCUUAGUAAGAUUACACAUGCAAGCAUCCCCGUUCCAGUGAGUUCACCCUC UAAAUCACCACGAUCAAAAGGGACAAGCAUCAAGCACGCAGCAAUGCAGCUCAAAACGCUUAGCCUAGCCACACCCCCAC GGGAAACAGCAGUGAUUAACCUUUAGCAAUAAACGAAAGUUUAACUAAGCUAUACUAACCCCAGGGUUGGUCAAUUUCGU GCCAGCCACCGCGGUCACACGAUUAACCCAAGUCAAUAGAAGCCGGCGUAAAGAGUGUUUUAGAUCACCCCCUCCCCAAU AAAGCUAAAACUCACCUGAGUUGUAAAAAACUCCAGUUGACACAAAAUAGACUACGAAAGUGGCUUUAACAUAUCUGAAC ACACAAUAGCUAAGACCCAAACUGGGAUUAGAUACCCCACUAUGCUUAGCCCUAAACCUCAACAGUUAAAUCAACAAAAC UGCUCGCCAGAACACUACGAGCCACAGCUUAAAACUCAAAGGACCUGGCGGUGCUUCAUAUCCCUCUAGAGGAGCCUGUU CUGUAAUCGAUAAACCCCGAUCAACCUCACCACCUCUUGCUCAGCCUAUAUACCGCCAUCUUCAGCAAACCCUGAUGAAG GCUACAAAGUAAGCGCAAGUACCCACGUAAAGACGUUAGGUCAAGGUGUAGCCCAUGAGGUGGCAAGAAAUGGGCUACAU UUUCUACCCCAGAAAACUACGAUAGCCCUUAUGAAACUUAAGGGUCGAAGGUGGAUUUAGCAGUAAACUGAGAGUAGAGU GCUUAGUUGAACAGGGCCCUGAAGCGCGUACACACCGCCCGUCACCCUCCUCAAGUAUACUUCAAAGGACAUUUAACUAA AACCCCUACGCAUUUAUAUAGAGGAGACAAGUCGUAACAUGGUAAGUGUACUGGAAAGUGCACUUGGACGAACC
28S ribosomal protein S2, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S2, mitochondrial
Theoretical weight (MDa):
0.033
Number of copies:
1
28S ribosomal protein S24, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S24, mitochondrial
Theoretical weight (MDa):
0.019
Number of copies:
1
28S ribosomal protein S5, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S5, mitochondrial
Theoretical weight (MDa):
0.048
Number of copies:
1
28S ribosomal protein S6, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S6, mitochondrial
Theoretical weight (MDa):
0.014
Number of copies:
1
28S ribosomal protein S7, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S7, mitochondrial
Theoretical weight (MDa):
0.028
Number of copies:
1
28S ribosomal protein S9, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S9, mitochondrial
Theoretical weight (MDa):
0.046
Number of copies:
1
28S ribosomal protein S10, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S10, mitochondrial
Theoretical weight (MDa):
0.023
Number of copies:
1
28S ribosomal protein S11, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S11, mitochondrial
Theoretical weight (MDa):
0.021
Number of copies:
1
28S ribosomal protein S12, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S12, mitochondrial
Theoretical weight (MDa):
0.015
Number of copies:
1
28S ribosomal protein S14, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S14, mitochondrial
Theoretical weight (MDa):
0.015
Number of copies:
1
28S ribosomal protein S15, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S15, mitochondrial
Theoretical weight (MDa):
0.03
Number of copies:
1
28S ribosomal protein S16, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S16, mitochondrial
Theoretical weight (MDa):
0.015
Number of copies:
1
28S ribosomal protein S17, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S17, mitochondrial
Theoretical weight (MDa):
0.015
Number of copies:
1
28S ribosomal protein S18b, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S18b, mitochondrial
Theoretical weight (MDa):
0.029
Number of copies:
1
28S ribosomal protein S18c, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S18c, mitochondrial
Theoretical weight (MDa):
0.016
Number of copies:
1
28S ribosomal protein S21, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S21, mitochondrial
Theoretical weight (MDa):
0.011
Number of copies:
1
28S ribosomal protein S22, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S22, mitochondrial
Theoretical weight (MDa):
0.041
Number of copies:
1
28S ribosomal protein S23, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S23, mitochondrial
Theoretical weight (MDa):
0.022
Number of copies:
1
28S ribosomal protein S25, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S25, mitochondrial
Theoretical weight (MDa):
0.02
Number of copies:
1
28S ribosomal protein S26, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S26, mitochondrial
Theoretical weight (MDa):
0.024
Number of copies:
1
28S ribosomal protein S27, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S27, mitochondrial
Theoretical weight (MDa):
0.048
Number of copies:
1
28S ribosomal protein S28, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S28, mitochondrial
Theoretical weight (MDa):
0.021
Number of copies:
1
28S ribosomal protein S29, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S29, mitochondrial
Theoretical weight (MDa):
0.046
Number of copies:
1
28S ribosomal protein S31, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S31, mitochondrial
Theoretical weight (MDa):
0.045
Number of copies:
1
28S ribosomal protein S33, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S33, mitochondrial
Theoretical weight (MDa):
0.013
Number of copies:
1
28S ribosomal protein S34, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S34, mitochondrial
Theoretical weight (MDa):
0.026
Number of copies:
1
28S ribosomal protein S35, mitochondrial [Human]
Protein type
Name:
28S ribosomal protein S35, mitochondrial
Theoretical weight (MDa):
0.037
Number of copies:
1
Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 [Human]
Protein type
Name:
Coiled-coil-helix-coiled-coil-helix domain-containing protein 1
Theoretical weight (MDa):
0.013
Number of copies:
1
Aurora kinase A-interacting protein [Human]
Protein type
Name:
Aurora kinase A-interacting protein
Theoretical weight (MDa):
0.022
Number of copies:
1
Pentatricopeptide repeat domain-containing protein 3, mitochondrial [Human]
Protein type
Name:
Pentatricopeptide repeat domain-containing protein 3, mitochondrial
Theoretical weight (MDa):
0.079
Number of copies:
1
A-site tRNA [Human]
Nucleic-acid type
Name:
A-site tRNA
Theoretical weight (MDa):
0.022
Type:
RNA
Structure:
OTHER
Synthetic:
false
Sequence:
UGGUAUAUAGUUUAAACAAAACGAAUGAUUUCGACUCAUUAAAUUAUGAUAAUCAUAUUUACCAACCA
P-site tRNA [Human]
Nucleic-acid type
Name:
P-site tRNA
Theoretical weight (MDa):
0.022
Type:
RNA
Structure:
OTHER
Synthetic:
false
Sequence:
UAGGGAAUAGUUUAAAAAACAGCUGACUUUCAAUCAGCAGAUGGAGGUUCAAUUCCUCCUUCCCUAACCA
mRNA [Human]
Nucleic-acid type
Name:
mRNA
Theoretical weight (MDa):
0.006
Type:
RNA
Structure:
OTHER
Synthetic:
false
Sequence:
UUUAAGAACGUGUUUAUUU
MAGNESIUM ION
Ligand type
Name:
MAGNESIUM ION
Theoretical weight (MDa):
0
Number of copies:
189
POTASSIUM ION
Ligand type
Name:
POTASSIUM ION
Theoretical weight (MDa):
0
Number of copies:
44
ZINC ION
Ligand type
Name:
ZINC ION
Theoretical weight (MDa):
0
Number of copies:
3
FE2/S2 (INORGANIC) CLUSTER
Ligand type
Name:
FE2/S2 (INORGANIC) CLUSTER
Theoretical weight (MDa):
0
Number of copies:
3
ADENOSINE-5'-TRIPHOSPHATE
Ligand type
Name:
ADENOSINE-5'-TRIPHOSPHATE
Theoretical weight (MDa):
0.001
Number of copies:
1
GUANOSINE-5'-TRIPHOSPHATE
Ligand type
Name:
GUANOSINE-5'-TRIPHOSPHATE
Theoretical weight (MDa):
0.001
Number of copies:
1
water
Ligand type
Name:
water
Theoretical weight (MDa):
0
Number of copies:
470