Function and Biology Details
Reaction catalysed:
Angiotensin II + H(2)O = angiotensin-(1-7) + L-phenylalanine
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-144145 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Angiotensin-converting enzyme 2
Molecule details ›
Chains: B, D
Length: 805 amino acids
Theoretical weight: 92.56 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 805 amino acids
Theoretical weight: 92.56 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q9BYF1 (Residues: 1-805; Coverage: 100%)
Sequence domains:
Fibritin; Spike protein S1
Molecule details ›
Chains: E, F
Length: 266 amino acids
Theoretical weight: 29.49 KDa
Source organisms: Expression system: Homo sapiens
UniProt:
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
Length: 266 amino acids
Theoretical weight: 29.49 KDa
Source organisms: Expression system: Homo sapiens
UniProt:
- Canonical: P0DTC2 (Residues: 323-528; Coverage: 16%)
- Canonical: P10104 (Residues: 458-484; Coverage: 6%)
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
