› 7klj

X-ray diffraction
1.52Å resolution

Crystal structure of the WD-repeat domain of human KIF21A

Released:
DOI: 10.2210/pdb7klj/pdb
PDB entry 7klj coloured by chain, front view.
PDB entry 7klj coloured by chain, side view.
PDB entry 7klj coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Zeng H, Dong A, Loppnau P, Hutchinson A, Seitova A, Edwards AM, Arrowsmith CH, Halabelian L, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182270 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kinesin-like protein KIF21A Chains: A, B
Molecule details ›
Chains: A, B
Length: 335 amino acids
Theoretical weight: 36.75 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q7Z4S6 (Residues: 1337-1653; Coverage: 19%)
Gene names: KIAA1708, KIF2, KIF21A
Sequence domains: WD domain, G-beta repeat

Ligands and Environments

2 bound ligands:
Ligand EDO 2 x EDO
Ligand UNX 5 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P21
Unit cell:
a: 55.275Å b: 67.067Å c: 79.88Å
α: 90° β: 94.43° γ: 90°
R-values:
R R work R free
0.17 0.17 0.185
Expression system: Spodoptera frugiperda

Quick links