› 7k7a

Solution NMR

Transmembrane structure of TNFR1

Released:
DOI: 10.2210/pdb7k7a/pdb
PDB entry 7k7a coloured by chain, ensemble of 15 models, front view.
PDB entry 7k7a coloured by chain, ensemble of 15 models, side view.
PDB entry 7k7a coloured by chain, ensemble of 15 models, top view.
Source organism: Homo sapiens
Primary publication:
The Diversity and Similarity of Transmembrane Trimerization of TNF Receptors.
Zhao L, Fu Q, Pan L, Piai A, Chou JJ
Front Cell Dev Biol 8 569684 (2020)
PMID: 33163490

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148578 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tumor necrosis factor receptor superfamily member 1A, membrane form Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 30 amino acids
Theoretical weight: 3.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P19438 (Residues: 209-238; Coverage: 7%)
Gene names: TNFAR, TNFR1, TNFRSF1A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 9%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

3 review citations

The TWEAK/Fn14/CD163 axis-implications for metabolic disease.
Ratajczak et al. (2022)
2 more

6 mentions without citation

A Bibliometric and In Silico-Based Analysis of Anti-Lung Cancer Compounds from Sea Cucumber.
Zare et al. (2023)
5 more