› 7cdz

X-ray diffraction
1.8Å resolution

Crystal structure of 2019-nCoV nucleocapsid N-terminal domain (NTD) protein

Released:
DOI: 10.2210/pdb7cdz/pdb
PDB entry 7cdz coloured by chain, front view.
PDB entry 7cdz coloured by chain, side view.
PDB entry 7cdz coloured by chain, top view.
Source organism: Severe acute respiratory syndrome coronavirus 2
Primary publication:
Structures of the SARS-CoV-2 nucleocapsid and their perspectives for drug design.
Peng Y, Du N, Lei Y, Dorje S, Qi J, Luo T, Gao GF, Song H
EMBO J 39 e105938 (2020)
PMID: 32914439

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-144998 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoprotein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 137 amino acids
Theoretical weight: 15.2 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P0DTC9 (Residues: 44-174; Coverage: 31%)
Gene name: N
Sequence domains: Coronavirus nucleocapsid

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P21
Unit cell:
a: 59.266Å b: 55.43Å c: 85.68Å
α: 90° β: 95.382° γ: 90°
R-values:
R R work R free
0.199 0.197 0.227
Expression system: Escherichia coli BL21

Quick links

Citations

23 review citations

Lessons learned 1 year after SARS-CoV-2 emergence leading to COVID-19 pandemic.
To et al. (2021)
22 more

21 mentions without citation

A Comprehensive Review about the Molecular Structure of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Insights into Natural Products against COVID-19.
Saied et al. (2021)
20 more