› 7bt7

Electron Microscopy
3.8Å resolution

F-actin-ADP complex structure

Released:
DOI: 10.2210/pdb7bt7/pdb
PDB entry 7bt7 coloured by chain, front view.
PDB entry 7bt7 coloured by chain, side view.
PDB entry 7bt7 coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Structural insights into actin filament recognition by commonly used cellular actin markers.
Kumari A, Kesarwani S, Javoor MG, Vinothkumar KR, Sirajuddin M
EMBO J 39 e104006 (2020)
PMID: 32567727
Related structures: EMD-30171

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159349 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Actin, alpha skeletal muscle Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 377 amino acids
Theoretical weight: 42.1 KDa
Source organism: Gallus gallus
UniProt:
  • Canonical: P68139 (Residues: 1-377; Coverage: 100%)
Gene names: ACTA, ACTA1
Sequence domains: Actin

Ligands and Environments

2 bound ligands:
Ligand MG 5 x MG
Ligand ADP 5 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.8Å
Relevant EMDB volumes: EMD-30171

Quick links

Citations

6 review citations

Actin-Associated Proteins and Small Molecules Targeting the Actin Cytoskeleton.
Gao et al. (2022)
5 more

4 mentions without citation

Structural insights into actin filament recognition by commonly used cellular actin markers.
Kumari et al. (2020)
3 more