7bep

X-ray diffraction
2.61Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-209701 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (6 distinct):
Spike protein S1 Chains: C, E
Molecule details ›
Chains: C, E
Length: 205 amino acids
Theoretical weight: 23.15 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 333-528; Coverage: 16%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
COVOX-384 heavy chain Chains: A, D
Molecule details ›
Chains: A, D
Length: 243 amino acids
Theoretical weight: 26.09 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
COVOX-384 light chain Chains: B, F
Molecule details ›
Chains: B, F
Length: 227 amino acids
Theoretical weight: 24.53 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
S309 heavy chain Chains: G, H
Molecule details ›
Chains: G, H
Length: 232 amino acids
Theoretical weight: 24.82 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
S309 light chain Chains: I, L
Molecule details ›
Chains: I, L
Length: 214 amino acids
Theoretical weight: 23.2 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN, FUC
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P212121
Unit cell:
a: 108.76Å b: 113.221Å c: 302.773Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.202 0.241
Expression system: Homo sapiens