7aic

Electron Microscopy
5Å resolution

MutS-MutL in clamp state (kinked clamp domain)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-121069 (preferred)
Entry contents:
2 distinct polypeptide molecules
2 distinct DNA molecules
Macromolecules (4 distinct):
DNA mismatch repair protein MutS Chains: A, B
Molecule details ›
Chains: A, B
Length: 853 amino acids
Theoretical weight: 95.27 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
  • Canonical: P23909 (Residues: 1-853; Coverage: 100%)
Gene names: JW2703, b2733, fdv, mutS
Sequence domains:
DNA mismatch repair protein MutL Chain: C
Molecule details ›
Chain: C
Length: 351 amino acids
Theoretical weight: 39.25 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
  • Canonical: P23367 (Residues: 1-331; Coverage: 54%)
Gene names: JW4128, b4170, mutL
Sequence domains:
DNA (30-MER) Chain: D
Molecule details ›
Chain: D
Length: 30 nucleotides
Theoretical weight: 9.3 KDa
DNA (30-MER) Chain: E
Molecule details ›
Chain: E
Length: 30 nucleotides
Theoretical weight: 9.14 KDa

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution:
Relevant EMDB volumes: EMD-11795
Expression system: Escherichia coli