› 6z43

Electron Microscopy
3.3Å resolution

Cryo-EM Structure of SARS-CoV-2 Spike : H11-D4 Nanobody Complex

Released:
DOI: 10.2210/pdb6z43/pdb
PDB entry 6z43 coloured by chain, front view.
PDB entry 6z43 coloured by chain, side view.
PDB entry 6z43 coloured by chain, top view.
Source organisms:
Entry authors: Ruza RR, Duyvesteyn HME, Shah P, Carrique L, Ren J, Malinauskas T, Zhou D, Stuart DI, Naismith JH
Related structures: EMD-11068

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-210129 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1288 amino acids
Theoretical weight: 142.4 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-1208; Coverage: 95%)
Gene names: 2, S
Sequence domains:
Nanobody Chains: X, Y, Z
Molecule details ›
Chains: X, Y, Z
Length: 151 amino acids
Theoretical weight: 16.68 KDa
Source organism: Lama glama
Expression system: Escherichia coli

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand NAG 26 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.3Å
Relevant EMDB volumes: EMD-11068
Expression systems:
  • Homo sapiens
  • Escherichia coli

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