› 6z2c

X-ray diffraction
1.8Å resolution

Engineered lipocalin C3A5 in complex with a transition state analog

Released:
DOI: 10.2210/pdb6z2c/pdb
PDB entry 6z2c coloured by chain, front view.
PDB entry 6z2c coloured by chain, side view.
PDB entry 6z2c coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Skerra A, Eichinger A

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160356 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neutrophil gelatinase-associated lipocalin Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 188 amino acids
Theoretical weight: 21.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P80188 (Residues: 21-198; Coverage: 100%)
Gene names: HNL, LCN2, NGAL
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family

Ligands and Environments

1 bound ligand:
Ligand Q5E 3 x Q5E
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P2
Unit cell:
a: 96.385Å b: 39.034Å c: 96.385Å
α: 90° β: 120° γ: 90°
R-values:
R R work R free
0.162 0.161 0.19
Expression system: Escherichia coli

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