› 6wjz

X-ray diffraction
1.8Å resolution

Crystal structure of human ribokinase in complex with AMPCP

Released:
DOI: 10.2210/pdb6wjz/pdb
PDB entry 6wjz coloured by chain, front view.
PDB entry 6wjz coloured by chain, side view.
PDB entry 6wjz coloured by chain, top view.
Source organism: Homo sapiens
Entry author: Park J

Function and Biology Details

Reaction catalysed: 
ATP + D-ribose = ADP + D-ribose 5-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190599 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribokinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 317 amino acids
Theoretical weight: 33.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9H477 (Residues: 14-322; Coverage: 96%)
Gene names: RBKS, RBSK
Sequence domains: pfkB family carbohydrate kinase

Ligands and Environments

4 bound ligands:
Ligand A12 2 x A12
Ligand GOL 6 x GOL
Ligand NA 2 x NA
Ligand MG 2 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P21
Unit cell:
a: 46.11Å b: 71.86Å c: 91.43Å
α: 90° β: 91.78° γ: 90°
R-values:
R R work R free
0.154 0.152 0.186
Expression system: Escherichia coli BL21(DE3)

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