› 6vqq

Electron Microscopy
2.56Å resolution

CryoEM Structure of the Plasmodium falciparum transporter PfFNT

Released:
DOI: 10.2210/pdb6vqq/pdb
PDB entry 6vqq coloured by chain, front view.
PDB entry 6vqq coloured by chain, side view.
PDB entry 6vqq coloured by chain, top view.
Source organism: Plasmodium falciparum 3D7
Primary publication:
Structural basis of transport and inhibition of the Plasmodium falciparum transporter PfFNT.
Lyu M, Su CC, Kazura JW, Yu EW
EMBO Rep 22 e51628 (2021)
PMID: 33471955
Related structures: EMD-21354

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131263 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Formate-nitrite transporter Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 309 amino acids
Theoretical weight: 34.49 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Homo sapiens
UniProt:
  • Canonical: O77389 (Residues: 1-309; Coverage: 100%)
Gene name: PF3D7_0316600
Sequence domains: Formate/nitrite transporter

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.56Å
Relevant EMDB volumes: EMD-21354
Expression system: Homo sapiens

Quick links

Citations

3 review citations

Plasmodium 6-Cysteine Proteins: Functional Diversity, Transmission-Blocking Antibodies and Structural Scaffolds.
Lyons et al. (2022)
2 more

3 mentions without citation

Local Attraction of Substrates and Co-Substrates Enhances Weak Acid and Base Transmembrane Transport.
Epalle et al. (2022)
2 more